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US-2024390271-A1 · Nov 28, 2024 · US
Ribonucleic acid binding motif protein 20 sequence variants
US9045554B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9045554-B2 |
| Application number | US-201314032043-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 19, 2013 |
| Priority date | May 12, 2010 |
| Publication date | Jun 2, 2015 |
| Grant date | Jun 2, 2015 |
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Abstract
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This document relates to methods and materials for using nucleic acid and amino acid sequence variants of ribonucleic acid binding motif protein 20 (RBM20). For example, methods and materials for using nucleic acid sequence variants and/or their corresponding amino acid variants of RBM20 that are associated with dilated cardiomyopathy to identify mammals (e.g., humans) at risk of having dilated cardiomyopathy that is likely to progress to heart failure are provided.
First claim
Opening claim text (preview).
What is claimed is: 1. A fusion nucleic acid comprising a ribonucleic acid binding motif protein 20 (RBM20) nucleic acid sequence encoding a fragment of a RBM20 polypeptide that is 22 to 100 amino acid residues in length and a nucleic acid sequence heterologous to said RBM20 nucleic acid sequence, wherein said fragment of said RBM20 polypeptide comprises a mutation with respect to a reference sequence, wherein said reference sequence is set forth in SEQ ID NO:3, wherein said mutati…
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Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
- C07K14/47Primary
Chemistry & Metallurgy · mapped topic
- A61B5/0071Primary
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US9045554B2 cover?
- This document relates to methods and materials for using nucleic acid and amino acid sequence variants of ribonucleic acid binding motif protein 20 (RBM20). For example, methods and materials for using nucleic acid sequence variants and/or their corresponding amino acid variants of RBM20 that are associated with dilated cardiomyopathy to identify mammals (e.g., humans) at risk of having dilated…
- Who is the assignee on this patent?
- Mayo Foundation
- What technology area does this patent fall under?
- Primary CPC classification C07K14/47. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).