TARGET-BASED METHOD FOR HIGH-THROUGHPUT AND SUBCLASS SPECIFIC IgG GLYCAN PROFILING IN HUMAN PLASMA
US-2024353417-A1 · Oct 24, 2024 · US
Disulfide stabilized antibodies and fragments thereof
US9045529B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9045529-B2 |
| Application number | US-201113637209-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 25, 2011 |
| Priority date | Mar 25, 2010 |
| Publication date | Jun 2, 2015 |
| Grant date | Jun 2, 2015 |
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Abstract
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The present disclosure provides an antibody or antibody fragment comprising at least one Fab molecule, wherein the light chain variable region, V L and the heavy chain region, V H of the Fab molecule are linked by one or more disulfide bonds, and use of the same in treatment or prophylaxis.
First claim
Opening claim text (preview).
The invention claimed is: 1. An antibody or antibody fragment comprising at least one Fab molecule, wherein said fab molecule comprises one or more disulfide bonds present between variable domains of heavy and light chain pairing therein and wherein no disulfide bond is present between heavy and light chain constant domains of said Fab molecule. 2. The antibody or antibody fragment according to claim 1 , wherein the antibody or antibody fragment is selected fro…
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Chemistry & Metallurgy · mapped topic
- C07K16/00Primary
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US9045529B2 cover?
- The present disclosure provides an antibody or antibody fragment comprising at least one Fab molecule, wherein the light chain variable region, V L and the heavy chain region, V H of the Fab molecule are linked by one or more disulfide bonds, and use of the same in treatment or prophylaxis.
- Who is the assignee on this patent?
- Humphreys David Paul, Ucb Pharma Sa
- What technology area does this patent fall under?
- Primary CPC classification C07K16/00. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).