Method of preparing oligomeric compounds using modified coupling protocols
US-2015368288-A1 · Dec 24, 2015 · US
N-pyrazole A2A receptor agonists
US9045519B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9045519-B2 |
| Application number | US-201314020736-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 6, 2013 |
| Priority date | Jun 22, 1999 |
| Publication date | Jun 2, 2015 |
| Grant date | Jun 2, 2015 |
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Abstract
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The present disclosure provides a process for the preparation of 2-adenosine N-pyrazole compounds exemplified by the structure shown below that are potent and selective agonists for A 2A adenosine receptor, compositions comprising these compounds, and methods for using these compound to stimulate mammalian coronary vasodilatation for imaging the heart.
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What we claim is: 1. A pharmaceutical composition comprising the compound of formula I and one or more pharmaceutical excipients in an aqueous buffered solution. 2. The pharmaceutical composition of claim 1 , wherein the pharmaceutical excipient is selected from the group consisting of polyvinylpyrrolidinone, gelatin, hydroxycellulose, acacia, polyeth…
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- What does patent US9045519B2 cover?
- The present disclosure provides a process for the preparation of 2-adenosine N-pyrazole compounds exemplified by the structure shown below that are potent and selective agonists for A 2A adenosine receptor, compositions comprising these compounds, and methods for using these compound to stimulate mammalian coronary vasodilatation for imaging the heart.
- Who is the assignee on this patent?
- Gilead Sciences Inc
- What technology area does this patent fall under?
- Primary CPC classification C07H19/16. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).