Purification of immunoglobulins

US9044740B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9044740-B2
Application numberUS-59400208-A
CountryUS
Kind codeB2
Filing dateMar 20, 2008
Priority dateMar 30, 2007
Publication dateJun 2, 2015
Grant dateJun 2, 2015

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Abstract

Official abstract text for this publication.

The present invention relates to a separation matrix comprised of a porous or non-porous support to which ligands have been immobilized, wherein said ligands comprise at least one aliphatic sulfamide. The invention also relates to a chromatography column that contains the described separation matrix, as well as to a method of isolating immunoglobulins, such as IgG, Fab fragments, fusion proteins containing immunoglobulins etc, by adsorption to a separation matrix that comprises the aliphatic sulfamide ligands of the invention.

First claim

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What is claimed is: 1. A separation matrix comprised of a support to which at least one ligand has been covalently immobilized, optionally via a spacer arm, wherein said ligand comprises one aliphatic sulfamide group described by the following formula: —N(R 1 )—S(O) 2 —N(R 2 )(R 3 )  (I) wherein R 1 , R 2 and R 3 are, independently from each other, either hydrogen or linear, optionally branched carbon chains, and wherein the content of aliphatic sulfamide groups is…

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What does patent US9044740B2 cover?
The present invention relates to a separation matrix comprised of a porous or non-porous support to which ligands have been immobilized, wherein said ligands comprise at least one aliphatic sulfamide. The invention also relates to a chromatography column that contains the described separation matrix, as well as to a method of isolating immunoglobulins, such as IgG, Fab fragments, fusion protein…
Who is the assignee on this patent?
Maloisel Jean-Luc, Johansson Bo-Lennart, Ge Healthcare Bio Sciences Ab
What technology area does this patent fall under?
Primary CPC classification B01J20/289. Mapped technology areas include Operations & Transport.
When was this patent published?
Publication date Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).