Use of delta tocopherol for the treatment of lysosomal storage disorders

US9044451B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9044451-B2
Application numberUS-201113810774-A
CountryUS
Kind codeB2
Filing dateJul 19, 2011
Priority dateJul 19, 2010
Publication dateJun 2, 2015
Grant dateJun 2, 2015

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  2. Abstract

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  5. First independent claim

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Abstract

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This disclosure relates generally to the treatment of lysosomal storage disorders. Specifically, the disclosure relates to a novel use of delta tocopherol in the treatment of diseases and conditions related to lysosomal storage disorders. Included in the present disclosure is a method for the modulation of cholesterol recycling. Further, the disclosure relates to conditions such as Niemann-Pick type C disease, Farber disease, Niemann-Pick type A disease, Wolman disease and Tay Sachs disease. Further included in the present disclosure is a method for treating lysosomal storage disorders comprising the administration of delta tocopherol. Further included in the present disclosure is a method for treating lysosomal storage disorders comprising the administration of delta tocopherol in combination with cyclodextrin to a patient in need thereof.

First claim

Opening claim text (preview).

What is claimed is: 1. A method for treating lysosomal storage disorder comprising administering to a subject in need thereof a pharmaceutically effective composition comprising δ tocopherol, wherein the composition does not comprise α tocopherol. 2. The method of claim 1 , wherein the lysosomal storage disorder is selected from the group consisting of Niemann-Pick Type C disease, Niemann-Pick Type A disease, Wolman disease, Farber disease, and Tay Sachs diseas…

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What does patent US9044451B2 cover?
This disclosure relates generally to the treatment of lysosomal storage disorders. Specifically, the disclosure relates to a novel use of delta tocopherol in the treatment of diseases and conditions related to lysosomal storage disorders. Included in the present disclosure is a method for the modulation of cholesterol recycling. Further, the disclosure relates to conditions such as Niemann-Pick…
Who is the assignee on this patent?
Zheng Wei, Marugan Juan Jose, Liu Ke, and 3 more
What technology area does this patent fall under?
Primary CPC classification A61K31/355. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).