Sirtuin modulating compounds and applications thereof
US-2024228431-A1 · Jul 11, 2024 · US
US9040539B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9040539-B2 |
| Application number | US-201113697806-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 18, 2011 |
| Priority date | May 19, 2010 |
| Publication date | May 26, 2015 |
| Grant date | May 26, 2015 |
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A process for the preparation of a chiral compound, in particular posaconazole, wherein the process comprises mixing and reacting the compounds of formula (I) Y 3 —NH 2 ; of formula (IIa) 0=C═N—Y 0 and/or of formula (IIb) and of formula (III) in a solvent in any order to obtain a reaction mixture containing a chiral compound of formula (IV) and/or formula (V).
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The invention claimed is: 1. An optionally crystalline chiral compound of formula (IVa) or a salt thereof, wherein R 1 is an alkyl residue having from 1 to 6 carbon atoms and wherein —R is —H or the hydroxyl protecting group —SiR a R b R c , where R a , R b and R c are the same or different and selected from the group consisting of optionally suitably substituted a…
Human Necessities · mapped topic
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