Method of producing lauric acid-containing oil or fat
US-9222111-B2 · Dec 29, 2015 · US
US9040264B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9040264-B2 |
| Application number | US-201213435315-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 30, 2012 |
| Priority date | Mar 31, 2011 |
| Publication date | May 26, 2015 |
| Grant date | May 26, 2015 |
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The invention provides microorganisms such as cyanobacteria genetically engineered to express proteins that include transcription factor domains for upregulation of lipid biosynthetic pathways. In addition to expression a gene encoding a transcription factor domain protein, the recombinant microorganisms can express at least one exogenous gene that encodes a polypeptide for the production of a fatty acid, fatty acid derivative, or triglyceride. Also included are methods of producing a fatty acid, fatty acid derivative, or triglyceride using the engineered microorganisms described herein as well as nucleic acid molecules encoding novel transcription factor domain proteins.
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The invention claimed is: 1. A recombinant cyanobacterium comprising an exogenous nucleic acid molecule encoding a transcription factor domain protein, wherein the transcription factor domain protein has transcription factor activity and comprises an amino acid sequence having at least 85% amino acid sequence identity to the amino acid sequence of SEQ ID NO:4, SEQ ID NO:6, SEQ ID NO:10, or SEQ ID NO:12, and wherein the recombinant cyanobacterium produces a greater amount of at l…
Cross-Sectional Technologies · mapped topic
Chemistry & Metallurgy · mapped topic
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