Biocatalysts for ezetimibe synthesis

US9040262B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9040262-B2
Application numberUS-201113695856-A
CountryUS
Kind codeB2
Filing dateMay 4, 2011
Priority dateMay 4, 2010
Publication dateMay 26, 2015
Grant dateMay 26, 2015

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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Abstract

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The present disclosure relates to non-naturally occurring polypeptides useful for preparing Ezetimibe, polynucleotides encoding the polypeptides, and methods of using the polypeptides.

First claim

Opening claim text (preview).

What is claimed is: 1. A method for preparing compound of Formula (Ia) in diastereomeric excess wherein, X is C or S; R 1 is selected from —H, —F, —Cl, —Br, or —I; R 2 is selected from —H, —F, —Cl, —Br, —I, —CN, —OH (optionally protected with a hydroxyl protecting group), —CH 2 NH 2 (optionally protected with a nitrogen protecting group), and an…

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What does patent US9040262B2 cover?
The present disclosure relates to non-naturally occurring polypeptides useful for preparing Ezetimibe, polynucleotides encoding the polypeptides, and methods of using the polypeptides.
Who is the assignee on this patent?
Crowe Michael, Alvizo Oscar, Behrouzian Behnaz, and 10 more
What technology area does this patent fall under?
Primary CPC classification C07K14/47. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue May 26 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).