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Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
US9034875B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9034875-B2 |
| Application number | US-201313831184-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 14, 2013 |
| Priority date | May 26, 2009 |
| Publication date | May 19, 2015 |
| Grant date | May 19, 2015 |
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Abstract
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Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
First claim
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What is claimed is: 1. A method of treating lymphoblastic leukemia, in a patient, the method comprising administering to the patient a therapeutically effective amount of a compound, or a pharmaceutically acceptable salt thereof, wherein the compound is selected from the group consisting of: methyl trans-4-{[(4-{[4-(4-[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl piperazin-1-yl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoyl]sulfamoyl}-2-nitrophenyl)amino]methyl 1 cyclohe…
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Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
- C07D471/04Primary
Chemistry & Metallurgy · mapped topic
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Frequently asked questions
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- What does patent US9034875B2 cover?
- Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
- Who is the assignee on this patent?
- Abbvie Inc
- What technology area does this patent fall under?
- Primary CPC classification C07D471/04. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue May 19 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).