Ophthalmic composition for the treatment of visual disorders
US-2024335458-A1 · Oct 10, 2024 · US
Sulfated oxysterol and oxysterol sulfation by hydroxysterol sulfotransferase promote lipid homeostasis and liver proliferation
US9034859B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9034859-B2 |
| Application number | US-201213441241-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 6, 2012 |
| Priority date | Apr 6, 2011 |
| Publication date | May 19, 2015 |
| Grant date | May 19, 2015 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
Methods and compositions for the prevention and treatment of liver damage or disease in a subject in need thereof are provided. The methods involve providing the sulfated oxysterol 25-hydroxycholesterol-3-sulfate (25HC3S) to the subject e.g. by 1) administering 25HC3S to the subject; or 2) overexpressing, in the subject, the hydroxysterol sulfotransferase enzyme SULT2B1b, which catalyzes the sulfation of 25-hydroxycholesterol (25HC) to form 25HC3S.
First claim
Opening claim text (preview).
I claim: 1. A method for promoting liver cell proliferation or liver tissue regeneration in a subject, comprising: i) identifying a subject in need of at least one of liver cell proliferation and liver tissue regeneration, and ii) elevating a level of 25-hydroxycholesterol-3-sulfate (25HC3S) in said subject by administering to said subject a composition comprising 25HC3S and a physiologically compatible carrier, wherein said subject does not have hyperlipidemia, and where…
Assignees
Inventors
Classifications
Patent family
Related publications grouped by family.
External sources
Next steps
Free tools are coming soon. Tell us what you want to track and we'll notify you.
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US9034859B2 cover?
- Methods and compositions for the prevention and treatment of liver damage or disease in a subject in need thereof are provided. The methods involve providing the sulfated oxysterol 25-hydroxycholesterol-3-sulfate (25HC3S) to the subject e.g. by 1) administering 25HC3S to the subject; or 2) overexpressing, in the subject, the hydroxysterol sulfotransferase enzyme SULT2B1b, which catalyzes the su…
- Who is the assignee on this patent?
- Ren Shunlin, Univ Virginia Commonwealth
- What technology area does this patent fall under?
- Primary CPC classification A61K31/575. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue May 19 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).