Nucleic acids targeting TCTP for use in the treatment of chemo- or hormone-resistant cancers

US9034840B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9034840-B2
Application numberUS-201113994862-A
CountryUS
Kind codeB2
Filing dateDec 19, 2011
Priority dateDec 17, 2010
Publication dateMay 19, 2015
Grant dateMay 19, 2015

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Abstract

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The present invention concerns a TCTP antagonist, in particular a nucleic acid targeting an m RNA encoding Translationally-Controlled Tumor Protein (TCTP), wherein said nucleic acid is capable of reducing the amount of TCTP in cells, for use in the treatment or prevention of hormone-independent cancer or chemo-resistant cancer, such as an androgen-independent prostate cancer.

First claim

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The invention claimed is: 1. A method for treating cancer comprising the step of administering an effective amount of a Translationally-Controlled Tumor Protein (TCTP) antagonist to an individual in need thereof, wherein said antagonist is a nucleic acid targeting a mRNA encoding TCTP, wherein said nucleic acid is capable of reducing the amount of TCTP in cells, and wherein said cancer is a hormone-independent cancer or chemo-resistant cancer. 2. The method of…

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What does patent US9034840B2 cover?
The present invention concerns a TCTP antagonist, in particular a nucleic acid targeting an m RNA encoding Translationally-Controlled Tumor Protein (TCTP), wherein said nucleic acid is capable of reducing the amount of TCTP in cells, for use in the treatment or prevention of hormone-independent cancer or chemo-resistant cancer, such as an androgen-independent prostate cancer.
Who is the assignee on this patent?
Rocchi Palma, Baylot Virginie, Acunzo Julie, and 4 more
What technology area does this patent fall under?
Primary CPC classification A61K31/7088. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue May 19 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).