Methods and compositions for cancer treatment
US-2024424094-A1 · Dec 26, 2024 · US
US9034840B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9034840-B2 |
| Application number | US-201113994862-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 19, 2011 |
| Priority date | Dec 17, 2010 |
| Publication date | May 19, 2015 |
| Grant date | May 19, 2015 |
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The present invention concerns a TCTP antagonist, in particular a nucleic acid targeting an m RNA encoding Translationally-Controlled Tumor Protein (TCTP), wherein said nucleic acid is capable of reducing the amount of TCTP in cells, for use in the treatment or prevention of hormone-independent cancer or chemo-resistant cancer, such as an androgen-independent prostate cancer.
Opening claim text (preview).
The invention claimed is: 1. A method for treating cancer comprising the step of administering an effective amount of a Translationally-Controlled Tumor Protein (TCTP) antagonist to an individual in need thereof, wherein said antagonist is a nucleic acid targeting a mRNA encoding TCTP, wherein said nucleic acid is capable of reducing the amount of TCTP in cells, and wherein said cancer is a hormone-independent cancer or chemo-resistant cancer. 2. The method of…
Human Necessities · mapped topic
Human Necessities · mapped topic
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