Compositions and methods for immunooncology
US-2024417722-A1 · Dec 19, 2024 · US
Syndecan peptides and polypeptides as inhibitors of cancer
US9034828B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9034828-B2 |
| Application number | US-201313936872-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 8, 2013 |
| Priority date | Mar 14, 2013 |
| Publication date | May 19, 2015 |
| Grant date | May 19, 2015 |
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Abstract
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The invention provides for peptides from syndecan 4 and methods of use therefor. These peptides can inhibit α6β4 integrin interaction with EGFR, thereby preventing tumor cell growth and tissue invasion.
First claim
Opening claim text (preview).
What is claimed is: 1. A method of inhibiting the interaction of α6β 4 integrin on the surface of a cancer cell with EGFR in a subject comprising administering to said subject a peptide segment consisting of between 45 and 100 amino acid residues and comprising about 45 residues of SEQ ID NO:1 including residues 87-131 (SEQ ID NO: 4) such that said cancer cells are contacted by said peptide. 2. The method of claim 1 , wherein said cancer cell is a carcinoma, a…
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- A61K38/177Primary
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
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Frequently asked questions
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- What does patent US9034828B2 cover?
- The invention provides for peptides from syndecan 4 and methods of use therefor. These peptides can inhibit α6β4 integrin interaction with EGFR, thereby preventing tumor cell growth and tissue invasion.
- Who is the assignee on this patent?
- Wisconsin Alumni Res Found
- What technology area does this patent fall under?
- Primary CPC classification A61K38/177. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue May 19 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).