Sample preparation for spectroscopy analysis

Patent metadata

Field	Value
Publication number	US-9034278-B2
Application number	US-201213597418-A
Country	US
Kind code	B2
Filing date	Aug 29, 2012
Priority date	Mar 3, 2010
Publication date	May 19, 2015
Grant date	May 19, 2015

Abstract

A sample is cleaned up for spectroscopic analysis by receiving a slide substrate having the sample thereon, fixing the sample to a substrate surface of the slide substrate by applying heat to the slide substrate for a predetermined heating time and incubating the sample on the slide substrate for a predetermined incubation time after fixing the sample to the slide substrate. The sample is further cleaned by washing the sample on the slide substrate after the sample has been incubated and drying the sample by applying heat to the slide substrate for a predetermined drying time, wherein the sample on the slide substrate after drying has retained particles of interest and interferant particles are removed from the substrate. A substrate is also provided for sample collection, which is culturable and Raman silent.

First claim

What is claimed is:

1. An apparatus to clean a sample for spectroscopic analysis, comprising:
a sample fixing station;
an incubation station;
a washing station;
a drying station;
an automated stage that advances a slide substrate inserted onto the automated stage, between the sample fixing station, the incubation station, the washing station and the drying station;
a dispenser that dispenses a solution comprising an organic solvent that is selected to remove interferant…

Assignees

• Bartko Andrew P
• Gao Johnway
• Battelle Memorial Institute

Inventors

• Bartko Andrew P
• Gao Johnway

Classifications

• Y10T436/2575

  Cross-Sectional Technologies · mapped topic

• G01N1/30 Primary

  Physics · mapped topic

• G01N1/312 Primary

  Physics · mapped topic

• G01N35/00029 Primary

  Physics · mapped topic