Pyridazinedione-based heterobicyclic covalent linkers and methods and applications thereof
US-2024425465-A1 · Dec 26, 2024 · US
US9029367B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9029367-B2 |
| Application number | US-201414301358-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 11, 2014 |
| Priority date | Jun 18, 2013 |
| Publication date | May 12, 2015 |
| Grant date | May 12, 2015 |
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The present invention provides a compound of Formula III: Formula III wherein A is: and Z, R 1 , R 2 , R 3 , and R 4 are as defined herein, or a pharmaceutically acceptable salt thereof, which is useful for treating Alzheimer's disease.
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We claim: 1. A compound of the formula: wherein A is: Z is O; R 1 is H, F, Cl, CN, OCH 3 , OCH 2 CH 2 OCH 3 , R 2 is H, F, Cl, or CH 3 ;…
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