Synthetic peptide, and cosmetic composition or pharmaceutical composition and application thereof
US-2024352069-A1 · Oct 24, 2024 · US
US9029326B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9029326-B2 |
| Application number | US-201414160791-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 22, 2014 |
| Priority date | May 18, 2012 |
| Publication date | May 12, 2015 |
| Grant date | May 12, 2015 |
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A polypeptide, a nucleic acid molecule encoding the polypeptide and a pharmaceutical composition comprising the polypeptide are provided. The polypeptide is as defined in the description, can bind to insulin receptors, and is effective in reducing blood sugar, reducing glycated hemoglobin, and ameliorating hepato-renal disorders caused by diabetes.
Opening claim text (preview).
What is claimed is: 1. An isolated polypeptide consisting of the amino acid sequence of RYKYQX1X2YI (SEQ ID NO: 189) or a homologous amino acid sequence derived from the substitution of a single amino acid in SEQ ID NO: 189, wherein X1 is cysteine or tryptophan and X2 is phenylalanine or tryptophan. 2. The polypeptide as claimed in claim 1 , which has the amino acid sequence of SEQ ID NO: 189. 3. The polypeptide as claimed in claim 1 , wher…
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