NSAIDs DERIVATIVES AND USES THEREOF
US-2015376162-A1 · Dec 31, 2015 · US
Antioxidant nanosphere comprising [1,2]-dithiolane moieties
US9028874B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9028874-B2 |
| Application number | US-81119708-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 30, 2008 |
| Priority date | Jan 3, 2008 |
| Publication date | May 12, 2015 |
| Grant date | May 12, 2015 |
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Abstract
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The present invention is directed to multiple a-lipoic acid-containing hydrophobic compounds (mALAs) capable of acting as scavengers of free radicals, metals and reactive oxygen species (ROS). Methods of synthesizing novel antioxidant mALAs, spontaneous emulsification or nanoprecipitaion thereof to produce antioxidant nanospheres and their use in preventing or treating diseases or conditions caused by oxidative stress and other free radical mediated conditions are also described. Another aspect of this invention is the use of these antioxidant nanospheres for the preparation of antioxidant particulate delivery system of therapeutic agents.
First claim
Opening claim text (preview).
What is claimed is: 1. An antioxidant molecule represented by Formula I wherein X is selected from the group consisting of a substituted, unsubstituted, branched or unbranched chain of carbon atoms, and may optionally contain a heteroatom; Y is a moiety formed by esterification of the hydroxyl groups of a polyol selected from the group consisting of…
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Human Necessities · mapped topic
- C07D339/04Primary
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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- What does patent US9028874B2 cover?
- The present invention is directed to multiple a-lipoic acid-containing hydrophobic compounds (mALAs) capable of acting as scavengers of free radicals, metals and reactive oxygen species (ROS). Methods of synthesizing novel antioxidant mALAs, spontaneous emulsification or nanoprecipitaion thereof to produce antioxidant nanospheres and their use in preventing or treating diseases or conditions ca…
- Who is the assignee on this patent?
- Yu John S, Lee Bong Seop, Cedars Sinai Medical Center
- What technology area does this patent fall under?
- Primary CPC classification C07D339/04. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue May 12 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).