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Resorbable ceramics with controlled strength loss rates
US9028871B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9028871-B2 |
| Application number | US-29801207-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 25, 2007 |
| Priority date | Apr 25, 2006 |
| Publication date | May 12, 2015 |
| Grant date | May 12, 2015 |
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Abstract
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Particular aspects provide bioresorbable and biocompatible compositions for bioengineering, restoring or regenerating tissue or bone, comprising a three-dimensional porous or non-porous scaffold material comprising a calcium phosphate-based ceramic having at least one dopant therein selected from metal ion or ion dopants and metal oxide dopants, wherein the composition is sufficiently biocompatible to provide for a cell or tissue scaffold, and resorbable at a controlled resorption rate for controlled strength loss, depending on dopant composition, under body, body fluid or simulated body fluid conditions. Preferably, the at least one dopant is selected from the group consisting of Zn 2+ , Mg 2+ , Si 2+ , Na + , K + , Sr 2+ , Cu 2+ , Fe 3+ /Fe 2+ , Ag + , Ti 4+ , CO 3 2− , F − , MgO, ZnO, NaF, KF, FeO/Fe 2 O 3 , SrO, CuO, SiO 2 , TiO 2 , Ag 2 O and CaCO 3 , present in an amount between 0 and about 10 w %, from about 0.5 to about 5 w %, or from about 1 to about 3 w %, and methods of using same.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method of providing a biocompatible ceramic material for bioengineering, restoring, or regenerating a tissue, the method comprising: determining an ex vivo degradation rate of a plurality of biocompatible ceramic materials each including a three-dimensional scaffold ceramic material composed of calcium phosphate ceramic sintered with a dopant uniformly distributed therein; wherein determining the ex vivo degradation rate includes: placing the plur…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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- What does patent US9028871B2 cover?
- Particular aspects provide bioresorbable and biocompatible compositions for bioengineering, restoring or regenerating tissue or bone, comprising a three-dimensional porous or non-porous scaffold material comprising a calcium phosphate-based ceramic having at least one dopant therein selected from metal ion or ion dopants and metal oxide dopants, wherein the composition is sufficiently biocompat…
- Who is the assignee on this patent?
- Bose Susmita, Bandyopadhyay Amit, Univ Washington State
- What technology area does this patent fall under?
- Primary CPC classification A61L27/58. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue May 12 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).