Compositions, methods and uses for expression of enterobacterium-associated peptides

US9028809B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9028809-B2
Application numberUS-201013511652-A
CountryUS
Kind codeB2
Filing dateNov 24, 2010
Priority dateNov 24, 2009
Publication dateMay 12, 2015
Grant dateMay 12, 2015

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Abstract

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Embodiments of the present invention generally disclose methods, compositions and uses for generating and expressing enterobacterial-associated peptides. In some embodiments, enterobacterial-associated peptides include, but are not limited to plague-associated peptides. In certain embodiments, methods generally relate to making and using compositions of constructs including, but not limited to, attenuated or modified vaccinia virus vectors expressing enterobacterial-associated peptides. In other embodiments, vaccine compositions are reported of use in a subject.

First claim

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What is claimed is: 1. An immunogenic composition comprising: one or more constructs of live attenuated, modified vaccinia Ankara (MVA) viruses encoding: at least one V 307 peptide which is the C-terminally truncated low-calcium response V (LcrV) protein antigen of Yersinia pestis lacking its C-terminal amino acids 308 to 326 and a mammalian secretory signal sequence and a viral translational control sequence, wherein the mammalian secretory signal sequence is tissue plasmi…

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What does patent US9028809B2 cover?
Embodiments of the present invention generally disclose methods, compositions and uses for generating and expressing enterobacterial-associated peptides. In some embodiments, enterobacterial-associated peptides include, but are not limited to plague-associated peptides. In certain embodiments, methods generally relate to making and using compositions of constructs including, but not limited to,…
Who is the assignee on this patent?
Stinchcomb Dan T, Osorio Jorge E, Powell Timothy D, and 2 more
What technology area does this patent fall under?
Primary CPC classification A61K39/025. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue May 12 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).