Microneedle device, and method for enhancing the efficacy of influenza vaccine by using microneedle device

US9028463B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9028463-B2
Application numberUS-200913001995-A
CountryUS
Kind codeB2
Filing dateMay 22, 2009
Priority dateJun 30, 2008
Publication dateMay 12, 2015
Grant dateMay 12, 2015

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  5. First independent claim

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Abstract

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The present invention provides a method for enhancing the immunogenicity using a microneedle device capable of enhancing the immunogenicity of an influenza vaccine. According to the method for enhancing the immunogenicity using the present microneedle device, a microneedle device having microneedles made of polylactic acid, coated with an influenza vaccine composed of an antigen having type A strain (H1N1), type A strain (H3N2), and type B strain as active ingredients is brought into direct contact with the skin so as to transcutaneously administer the aforementioned influenza vaccine. After the transcutaneous administration, lauryl alcohol is applied to the site of the skin where the microneedle device has been brought into direct contact.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method for enhancing the efficacy of an influenza vaccine using a microneedle device for increasing IgG antibody titer and IgA antibody titer in a patient in need thereof comprising applying an adjuvant containing lauryl alcohol to an administration site after administering the influenza vaccine, wherein the microneedle device comprises a plurality of microneedles, and the microneedles are made of polylactic acid, capable of puncturing skin, arranged…

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What does patent US9028463B2 cover?
The present invention provides a method for enhancing the immunogenicity using a microneedle device capable of enhancing the immunogenicity of an influenza vaccine. According to the method for enhancing the immunogenicity using the present microneedle device, a microneedle device having microneedles made of polylactic acid, coated with an influenza vaccine composed of an antigen having type A s…
Who is the assignee on this patent?
Nozaki Chikateru, Kaminaka Kazuyoshi, Matsuda Junichi, and 5 more
What technology area does this patent fall under?
Primary CPC classification A61K39/145. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue May 12 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).