Vaccine composition for use against influenza
US-9220767-B2 · Dec 29, 2015 · US
US9028463B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9028463-B2 |
| Application number | US-200913001995-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 22, 2009 |
| Priority date | Jun 30, 2008 |
| Publication date | May 12, 2015 |
| Grant date | May 12, 2015 |
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The present invention provides a method for enhancing the immunogenicity using a microneedle device capable of enhancing the immunogenicity of an influenza vaccine. According to the method for enhancing the immunogenicity using the present microneedle device, a microneedle device having microneedles made of polylactic acid, coated with an influenza vaccine composed of an antigen having type A strain (H1N1), type A strain (H3N2), and type B strain as active ingredients is brought into direct contact with the skin so as to transcutaneously administer the aforementioned influenza vaccine. After the transcutaneous administration, lauryl alcohol is applied to the site of the skin where the microneedle device has been brought into direct contact.
Opening claim text (preview).
The invention claimed is: 1. A method for enhancing the efficacy of an influenza vaccine using a microneedle device for increasing IgG antibody titer and IgA antibody titer in a patient in need thereof comprising applying an adjuvant containing lauryl alcohol to an administration site after administering the influenza vaccine, wherein the microneedle device comprises a plurality of microneedles, and the microneedles are made of polylactic acid, capable of puncturing skin, arranged…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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