TARGET-BASED METHOD FOR HIGH-THROUGHPUT AND SUBCLASS SPECIFIC IgG GLYCAN PROFILING IN HUMAN PLASMA
US-2024353417-A1 · Oct 24, 2024 · US
Method for detecting molecules through mass spectrometry
US9018580B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9018580-B2 |
| Application number | US-201013496949-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 15, 2010 |
| Priority date | Sep 25, 2009 |
| Publication date | Apr 28, 2015 |
| Grant date | Apr 28, 2015 |
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Abstract
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A method for detecting at least one target molecule in a sample by mass spectrometry, comprising ionizing the molecules of the sample and then conducting the following steps (i) and (ii) n times, n being equal to 0, 1, 2, 3 or 4: (i) at least one ion obtained in the preceding step is selected, according to the target molecule, in a mass analyzer, and (ii) the ion thus selected is fragmented in a fragmentation cell; trapping at least two different sampled ions, when n is zero, or when n is other than zero, in a mass analyzer, the at least two ions thus trapped having a mass-to-charge ratio m/z characteristic of the target molecule; ejecting the trapped ions from the mass analyzer; and detecting the ejected ions ejected by means of a detection device. The method is characterized in that the characteristic ions are ejected simultaneously and detected simultaneously.
First claim
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The invention claimed is: 1. Method for detecting at least one target molecule in a sample by mass spectrometry, in which: a) the molecules of the sample are ionized, by means of at least one ionization device, so as to obtain molecular ions, b) the following steps (i) and (ii) are carried out n times, n being equal to 0, 1, 2, 3 or 4: (i) at least one ion obtained in the preceding step is selected, according to the target molecule, in a mass analyzer, and (ii) said at least…
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Electricity · mapped topic
Electricity · mapped topic
Electricity · mapped topic
- G01N33/6848Primary
Physics · mapped topic
Physics · mapped topic
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- What does patent US9018580B2 cover?
- A method for detecting at least one target molecule in a sample by mass spectrometry, comprising ionizing the molecules of the sample and then conducting the following steps (i) and (ii) n times, n being equal to 0, 1, 2, 3 or 4: (i) at least one ion obtained in the preceding step is selected, according to the target molecule, in a mass analyzer, and (ii) the ion thus selected is fragmented in …
- Who is the assignee on this patent?
- Lemoine Jéröme, Salvador Arnaud, Charrier Jean-Philippe, and 5 more
- What technology area does this patent fall under?
- Primary CPC classification G01N33/6848. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Apr 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).