Enzymes for producing non-straight-chain fatty acids
US-2015376659-A1 · Dec 31, 2015 · US
Production and secretion of fatty acids and fatty acid derivatives
US9017975B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9017975-B2 |
| Application number | US-201213629492-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 27, 2012 |
| Priority date | Sep 27, 2011 |
| Publication date | Apr 28, 2015 |
| Grant date | Apr 28, 2015 |
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Abstract
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The invention relates to acyl-CoA-independent methods of producing fatty alcohols in recombinant host cells engineered to express an alcohol-forming acyl-ACP reductase. The recombinant host cells may be photosynthetic microorganisms, such as cyanobacteria. Isolated nucleic acid molecules, vectors, and recombinant host cells expressing an alcohol-forming acyl-ACP reductase, and systems for producing fatty alcohols via an acyl-CoA-independent pathway, are also provided. Also provided are microorganisms engineered for the secretion of fatty acids and fatty acid derivatives, including fatty alcohols, and methods of producing fatty acid derivatives using such engineering microorganisms.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method of producing a fatty acid or fatty acid derivative, comprising: providing a recombinant prokaryotic microorganism that comprises: at least one non-native gene encoding a polypeptide that participates in the synthesis of a fatty acid or a fatty acid derivative; and at least one non-native gene encoding a VgrG protein of a Type VI secretion system (T6SS) of a Pseudomonas or Vibrio species, or a C-terminally truncated VgrG protein compris…
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Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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Frequently asked questions
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- What does patent US9017975B2 cover?
- The invention relates to acyl-CoA-independent methods of producing fatty alcohols in recombinant host cells engineered to express an alcohol-forming acyl-ACP reductase. The recombinant host cells may be photosynthetic microorganisms, such as cyanobacteria. Isolated nucleic acid molecules, vectors, and recombinant host cells expressing an alcohol-forming acyl-ACP reductase, and systems for produ…
- Who is the assignee on this patent?
- Synthetic Genomics Inc
- What technology area does this patent fall under?
- Primary CPC classification C12P7/6409. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).