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Method for the synthesis of porphyrin-phospholipid conjugates
US9017974B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9017974-B2 |
| Application number | US-201214125035-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 25, 2012 |
| Priority date | Jun 6, 2011 |
| Publication date | Apr 28, 2015 |
| Grant date | Apr 28, 2015 |
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Abstract
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There is herein described a nanovesicle comprising a bilayer of porphyrin-phospholipid conjugates. Each porphyrin-phospholipid conjugate comprises one porphyrin, porphyrin derivative or porphyrin analog covalently attached to a lipid side chain at one of the sn-1 or the sn-2 positions of one phospholipid. Further, the nanovesicle has a defined regioisomeric ratio of sn-1:sn-2 porphyrin-phospholipid conjugates.
First claim
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The invention claimed is: 1. A method for producing a composition of porphyrin-phospholipids conjugate from a mixture of sn-1 and sn-2 regioisomers of porphyrin-phospholipid conjugates, each of said regioisomers comprising one porphyrin, porphyrin derivative or porphyrin analog covalently attached to a lipid side chain at one of the sn-1 or the sn-2 positions of one phospholipid, wherein the composition has a defined regioisomeric ratio of sn-1:sn-2 porphyrin-phospholipid conjugate…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
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- What does patent US9017974B2 cover?
- There is herein described a nanovesicle comprising a bilayer of porphyrin-phospholipid conjugates. Each porphyrin-phospholipid conjugate comprises one porphyrin, porphyrin derivative or porphyrin analog covalently attached to a lipid side chain at one of the sn-1 or the sn-2 positions of one phospholipid. Further, the nanovesicle has a defined regioisomeric ratio of sn-1:sn-2 porphyrin-phosphol…
- Who is the assignee on this patent?
- Zheng Gang, Lovell Jonathan, Univ Health Network
- What technology area does this patent fall under?
- Primary CPC classification C12P17/182. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).