System and methods for performing saliva-based diagnostic screenings
US-2024420847-A1 · Dec 19, 2024 · US
5.9 kDa peptide immunoassay method
US9017959B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9017959-B2 |
| Application number | US-201013502198-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 13, 2010 |
| Priority date | Oct 28, 2009 |
| Publication date | Apr 28, 2015 |
| Grant date | Apr 28, 2015 |
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Abstract
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Disclosed is an immunoassay method whereby a 5.9 kDa peptide which results from the degradation of the α-E chain and α chain of human fibrinogens and which is used as a peptide marker for diagnosing hepatic disease can be specifically assayed in a biological sample containing contaminating peptides by bringing antibodies that recognize the N terminal of said peptide marker and antibodies that recognize the C terminal of said peptide marker into contact with said peptide marker, forming immune complexes of said peptide marker and the two antibodies, and immunoassaying the obtained immune complexes.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method of immunoassay for a peptide consisting of SEQ ID NO: 1, comprising: contacting a sample suspected of containing a mixture of peptides comprising the peptide consisting of SEQ ID NO: 1 and a peptide consisting of SEQ ID NO:4 fused to SEQ ID NO: 1, at the N-terminus of SEQ ID NO: 1, with an antibody or antibody fragment thereof recognizing the epitope of 1st to 17th amino acids of SEQ ID NO: 1 in the peptide of SEQ ID NO: 1, and with an antibod…
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Physics · mapped topic
Chemistry & Metallurgy · mapped topic
- G01N33/6893Primary
Physics · mapped topic
Physics · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US9017959B2 cover?
- Disclosed is an immunoassay method whereby a 5.9 kDa peptide which results from the degradation of the α-E chain and α chain of human fibrinogens and which is used as a peptide marker for diagnosing hepatic disease can be specifically assayed in a biological sample containing contaminating peptides by bringing antibodies that recognize the N terminal of said peptide marker and antibodies that r…
- Who is the assignee on this patent?
- Kikuchi Wataru, Sato Momoe, Noda Kenta, and 6 more
- What technology area does this patent fall under?
- Primary CPC classification G01N33/6893. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Apr 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).