Intestinal mononuclear phagocytes as prognostic biomarker for crohn's disease
US-2024425923-A1 · Dec 26, 2024 · US
US9017936B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9017936-B2 |
| Application number | US-89859010-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 5, 2010 |
| Priority date | Oct 6, 2009 |
| Publication date | Apr 28, 2015 |
| Grant date | Apr 28, 2015 |
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Methods and kits for identifying candidate anti-megakaryocyte agents are disclosed.
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What is claimed is: 1. A method of identifying an anti-megakaryocyte agent comprising: contacting, a cell capable of expressing TRB-3 with an agent to be tested for anti-megakaryocyte activity; measuring expression of TRB-3 in a cell contacted with the test agent; comparing the expression of TRB-3 in a cell contacted with the test agent to a control level of expression; assessing the anti-megakaryocyte activity of a test agent which increases the expression of TRB-3 in a cel…
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