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Phenyl-3-aza-bicyclo[3.1.0]hex-3-yl-methanones and the use thereof as medicament
US9012489B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9012489-B2 |
| Application number | US-201213560063-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 27, 2012 |
| Priority date | Aug 3, 2011 |
| Publication date | Apr 21, 2015 |
| Grant date | Apr 21, 2015 |
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Abstract
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Substituted phenyl-3-aza-bicyclo[3.1.0]hex-3-yl-methanones which are glycine transporter-1 (GlyT1) inhibitors. These are useful for the treatment of schizophrenia, Alzheimer's Disease and other neurological and psychiatric disorders.
First claim
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The invention claimed is: 1. A compound of the formula (I) wherein R 1 is selected from the group consisting of a) 5 or 6 membered moncyclic heteroaryl, having 1, 2, 3 or 4 heteroatoms independently selected from the group consisting of O, N and S(O)r, b) 5 or 6 membered moncyclic partially saturated heterocycloalkyl, having 1, 2 or 3 heteroatoms independently sel…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
- C07D413/04Primary
Chemistry & Metallurgy · mapped topic
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- What does patent US9012489B2 cover?
- Substituted phenyl-3-aza-bicyclo[3.1.0]hex-3-yl-methanones which are glycine transporter-1 (GlyT1) inhibitors. These are useful for the treatment of schizophrenia, Alzheimer's Disease and other neurological and psychiatric disorders.
- Who is the assignee on this patent?
- Giovannini Riccardo, Bertani Barbara, Ferrara Marco, and 4 more
- What technology area does this patent fall under?
- Primary CPC classification C07D413/04. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 21 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).