Quaternary heteroatom containing compounds
US-10035769-B2 · Jul 31, 2018 · US
US9012471B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9012471-B2 |
| Application number | US-93717709-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 10, 2009 |
| Priority date | Apr 11, 2008 |
| Publication date | Apr 21, 2015 |
| Grant date | Apr 21, 2015 |
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The present invention provides, inter alia, dihydropyridone compounds and compositions, including analogs of a vesicular monoamine transporter type 2 (VMAT2) antagonist. The present invention also provides methods of using such compounds/analogs for modulating glucose levels, and/or preventing, treating, or ameliorating the effects of diabetes and hyper-glycemia.
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What is claimed is: 1. A compound of formula II: wherein R 1 , R 2 , R 3 , R 8 and R 9 are independently selected from the group consisting of H, halogen, C 1 -C 8 alkyl, C 1 -C 8 alkenyl, and C 1 -C 8 alkynyl; R 4 and R 5 , which are attached to one or more positions of at least one carbon atom of the respective rings, are independently selected from the group con…
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