Immunomodulatory Combinations of Antigen and Drug-Lipid Conjugate
US-2024374734-A1 · Nov 14, 2024 · US
US9012437B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9012437-B2 |
| Application number | US-201313886465-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 3, 2013 |
| Priority date | Jul 5, 2000 |
| Publication date | Apr 21, 2015 |
| Grant date | Apr 21, 2015 |
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Methods for treating inflammation-mediated conditions of the eye are described, comprising: implanting into the vitreous of the eye of an individual a bioerodible implant comprising a steroidal anti-inflammatory agent and a bioerodible polymer, wherein the implant delivers the agent to the vitreous in an amount sufficient to reach a concentration equivalent to at least about 0.05 μg/ml dexamethasone within about 48 hours and maintains a concentration equivalent to at least about 0.03 μg/ml dexamethasone for at least about three weeks.
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What is claimed is: 1. A method for treating an inflammation-mediated condition of the eye comprising: implanting into the vitreous of the eye a bioerodible implant consisting of dexamethasone and a bioerodible polymer, wherein the implant delivers the dexamethasone to the vitreous in an amount sufficient to reach a concentration equivalent to at least about 0.05 μg/mL dexamethasone within about 48 hours, and maintains a concentration equivalent to at least about 0.03 μg/mL dexamet…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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