Genetically modified bacillus subtilis strain and use as a live delivery and production system
US-2024390433-A1 · Nov 28, 2024 · US
US9012227B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9012227-B2 |
| Application number | US-74231808-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 12, 2008 |
| Priority date | Dec 17, 2007 |
| Publication date | Apr 21, 2015 |
| Grant date | Apr 21, 2015 |
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The present invention relates to a cell, which has been genetically modified relative to its wild type, so that in comparison with its wild type it is able to produce more ω-aminocarboxylic acids, more ω-aminocarboxylic acid esters or more lactams derived from ω-aminocarboxylic acids, starting from carboxylic acids or carboxylic acid esters. Furthermore, the present invention relates to a method for the production of a genetically modified cell, the cells obtainable by this method, a method for the production of ω-aminocarboxylic acids, of ω-aminocarboxylic acid esters or of lactams derived from ω-aminocarboxylic acids, the ω-aminocarboxylic acids, ω-aminocarboxylic acid esters or lactams derived from ω-aminocarboxylic acids obtainable by this method, a method for the production of polyamides based on ω-aminocarboxylic acids or based on lactams and the polyamides obtainable by this method.
Opening claim text (preview).
The invention claimed is: 1. An isolated recombinant cell, which has been genetically modified relative to its wild type so that, in comparison to the wild type, the recombinant cell is able to produce more ω-aminocarboxylic acid, ω-aminocarboxylic acid esters, or more lactams derived from ω-aminocarboxylic acid, starting from carboxylic acids, or carboxylic acid esters, wherein the isolated recombinant cell comprises: (i) a first nucleic acid encoding a heterologous enzyme E I ,…
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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