Compositions and methods for islet cell transplants
US-2024269194-A1 · Aug 15, 2024 · US
Differentiation of human embryonic stem cells
US9012218B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9012218-B2 |
| Application number | US-60388909-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 22, 2009 |
| Priority date | Oct 31, 2008 |
| Publication date | Apr 21, 2015 |
| Grant date | Apr 21, 2015 |
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Abstract
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The present invention provides methods to promote the differentiation of pluripotent stem cells. In particular, the present invention provides a method to increase the expression of markers associated with the pancreatic endocrine lineage.
First claim
Opening claim text (preview).
What is claimed is: 1. A method of increasing the expression of markers associated with pancreatic endocrine cells comprising treating human pancreatic endocrine cells with medium comprising a sufficient amount of a TGF-β receptor agonist for about one to about five days to cause an increase in expression of markers associated with the pancreatic endocrine cells compared to pancreatic endocrine cells not treated with the TGF-β receptor agonist, wherein the method comprises an incre…
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Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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Frequently asked questions
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- What does patent US9012218B2 cover?
- The present invention provides methods to promote the differentiation of pluripotent stem cells. In particular, the present invention provides a method to increase the expression of markers associated with the pancreatic endocrine lineage.
- Who is the assignee on this patent?
- Rezania Alireza, Janssen Biotech Inc
- What technology area does this patent fall under?
- Primary CPC classification C12N5/0676. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 21 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).