Anti-bacterial peptides and methods of treating diseases using same

US9012152B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9012152-B2
Application numberUS-52254508-A
CountryUS
Kind codeB2
Filing dateJan 8, 2008
Priority dateJan 9, 2007
Publication dateApr 21, 2015
Grant dateApr 21, 2015

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  1. Title

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  2. Abstract

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  5. First independent claim

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Abstract

Official abstract text for this publication.

Isolated peptides comprising no more than ten amino acids and having anti-bacterial properties are disclosed. In one embodiment the peptides have a consensus amino acid sequence X 1 X 2 X 3 X 4 X 5 , wherein X 1 and X 5 comprise polar amino acids. In another embodiment, the peptides have a consensus amino acid sequence X 1 X 2 X 3 X 4 X 5 , wherein X 2 and X 4 are asparagine (N) residues and X 3 is tryptophan (W). Compositions comprising same are also disclosed and uses thereof.

First claim

Opening claim text (preview).

What is claimed is: 1. A method of killing bacteria which comprise the mazEF toxin-antitoxin module and which are in logarithmic growth, the method comprising contacting the bacteria with an effective amount of an isolated pentapeptide, comprising a consensus amino acid sequence X 1 X 2 X 3 X 4 X 5 , wherein both X 1 and X 5 comprise an amino acid independently selected from the group consisting of an asparagine residue and a glutamine residue wherein X 3 is a tryptophan residue…

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Classifications

  • C07K14/245Primary

    Chemistry & Metallurgy · mapped topic

  • Human Necessities · mapped topic

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What does patent US9012152B2 cover?
Isolated peptides comprising no more than ten amino acids and having anti-bacterial properties are disclosed. In one embodiment the peptides have a consensus amino acid sequence X 1 X 2 X 3 X 4 X 5 , wherein X 1 and X 5 comprise polar amino acids. In another embodiment, the peptides have a consensus amino acid sequence X 1 X 2 X 3 X 4 X 5 , wherein X 2 and X 4 are asparagine (N) residues an…
Who is the assignee on this patent?
Engelberg-Kulka Hanna, Kolodkin-Gal Ilana, Yissum Res Dev Co
What technology area does this patent fall under?
Primary CPC classification C07K14/245. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Apr 21 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).