Inhibitors of tyk2
US-2024425484-A1 · Dec 26, 2024 · US
Pyrimidone derivatives
US9006232B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9006232-B2 |
| Application number | US-201013389512-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 11, 2010 |
| Priority date | Aug 13, 2009 |
| Publication date | Apr 14, 2015 |
| Grant date | Apr 14, 2015 |
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Abstract
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A compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: wherein Z represents nitrogen atom or C—X; X represents hydrogen atom or fluorine atom; R 1 is hydrogen atom or a C 1 -C 3 alkyl group; L represents single bond or a C 1 -C 6 alkylene group which may be substituted; Y represents single bond, sulfur atom, oxygen atom, NH, or the like; R 2 represents hydrogen atom or a cyclic group which may be substituted, which is used for preventive and/or therapeutic treatment of a disease caused by abnormal activity of tau protein kinase 1 such as a neurodegenerative diseases (e.g. Alzheimer disease).
First claim
Opening claim text (preview).
The invention claimed is: 1. A compound represented by general formula (I): wherein: Z represents a nitrogen atom or C—X; X represents a hydrogen atom or a fluorine atom; R 1 is a C 1 -C 3 alkyl group; and L, Y and R 2 are groups as represented by (1) or (2): (1) L is a single bond or a C 1 -C 6 alkylene group which may have 1 to 4 substituents which are the s…
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- What does patent US9006232B2 cover?
- A compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: wherein Z represents nitrogen atom or C—X; X represents hydrogen atom or fluorine atom; R 1 is hydrogen atom or a C 1 -C 3 alkyl group; L represents single bond or a C 1 -C 6 alkylene group which may be substituted; Y represents single bond, sulfur atom, oxygen atom, NH, or the…
- Who is the assignee on this patent?
- Nakayama Kazuki, Sakai Daiki, Watanabe Kazutoshi, and 3 more
- What technology area does this patent fall under?
- Primary CPC classification C07D401/12. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 14 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).