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Thieno[3,2-d]pyrimidine derivatives having inhibitory activity on protein kinases
US8999973B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8999973-B2 |
| Application number | US-201113520656-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 31, 2011 |
| Priority date | Jan 29, 2010 |
| Publication date | Apr 7, 2015 |
| Grant date | Apr 7, 2015 |
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Abstract
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The present invention relates to a thieno[3,2-d]pyrimidine derivative of formula (I), or a pharmaceutically acceptable salt, hydrate or solvate thereof, which has an excellent inhibitory activity on protein kinases, and a pharmaceutical composition comprising the same is effective in preventing or treating abnormal cell growth diseases.
First claim
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What is claimed is: 1. A thieno[3,2-d]compound of formula (I), and a pharmaceutically acceptable salt thereof: wherein, Y is —CH═CR 1 —, —CC—, or —C(═O)NR 1 —; L is —C(═O)NR 2 —, —NR 2 C(═O)—, or —NR 2 C(═O)NR 2 —; R 1 and R 2 are each independently H, C 1-6 alkyl, or C 3-8 cycloalkyl; R is H, halogen, methyl, or methoxy; E is…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
- C07D495/04Primary
Chemistry & Metallurgy · mapped topic
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- What does patent US8999973B2 cover?
- The present invention relates to a thieno[3,2-d]pyrimidine derivative of formula (I), or a pharmaceutically acceptable salt, hydrate or solvate thereof, which has an excellent inhibitory activity on protein kinases, and a pharmaceutical composition comprising the same is effective in preventing or treating abnormal cell growth diseases.
- Who is the assignee on this patent?
- Son Jung Beom, Jung Seung Hyun, Choi Wha Ii, and 17 more
- What technology area does this patent fall under?
- Primary CPC classification C07D495/04. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).