Modulators of G-Protein Coupled Receptors
US-2024383960-A1 · Nov 21, 2024 · US
Analogues of glucose-dependent insulinotropic polypeptide (GIP) modified at N-terminal
US8999940B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8999940-B2 |
| Application number | US-200913057966-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 7, 2009 |
| Priority date | Aug 7, 2008 |
| Publication date | Apr 7, 2015 |
| Grant date | Apr 7, 2015 |
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Abstract
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There is provided a novel series of analogues of glucose-dependent insulinotropic polypeptide compounds, pharmaceutical compositions containing said compounds, and the use of said compounds as GIP-receptor agonists or antagonists for treatment of GIP-receptor mediated conditions, such as non-insulin dependent diabetes mellitus and obesity.
First claim
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What is claimed is: 1. A compound of formula (I), (R 2 R 3 )-A 1 -A 2 -A 3 -A 4 -A 5 -A 6 -A 7 -A 8 -A 9 -A 10 -A 11 -A 12 -A 13 -A 14 -A 15 -A 16 -A 17 -A 18 -A 19 -A 20 A 21 -A 22 -A 23 -A 24 -A 25 -A 26 -A 27 -A 28 -A 29 -A 30 -A 31 -A 32 -A 33 -A 34 -A 35 -A 36 -A 37 -A 38 -A 39 -A 40 -A 41 -A 42 -A 43 -R 1 , (I) wherein: A 1 is Cpa, His, 4Hppa, 2-Pal, 3-Pal, 4-Pal, 3Br-Phe, 4CF 3 -Phe, 3Cl-Phe, 4CN-Phe, 3F-Phe, 4F-Phe, 3,4F-Phe, 3,5F-Phe, 3,4,5F-Phe, 4Me-Phe,…
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Frequently asked questions
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- What does patent US8999940B2 cover?
- There is provided a novel series of analogues of glucose-dependent insulinotropic polypeptide compounds, pharmaceutical compositions containing said compounds, and the use of said compounds as GIP-receptor agonists or antagonists for treatment of GIP-receptor mediated conditions, such as non-insulin dependent diabetes mellitus and obesity.
- Who is the assignee on this patent?
- Dong Zheng Xin, Ipsen Pharma Sas
- What technology area does this patent fall under?
- Primary CPC classification C07K14/605. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).