Signal peptides for increased protein secretion
US-2024141363-A1 · May 2, 2024 · US
US8999705B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8999705-B2 |
| Application number | US-201213720866-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 19, 2012 |
| Priority date | Sep 15, 2006 |
| Publication date | Apr 7, 2015 |
| Grant date | Apr 7, 2015 |
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This invention provides nucleic acids and proteins involved in oligosaccharide modification in the species Bifidobacteria. The invention provides methods for utilizing the proteins of the invention to generate human milk oligosaccharides or oligosaccharide mimics. The invention also provides compositions containing the human milk oligosaccharides or oligosaccharide mimics and methods for use.
Opening claim text (preview).
What is claimed is: 1. An isolated nucleic acid comprising a recombinant expression cassette comprising a promoter operably linked to a heterologous polynucleotide encoding a sialidase polypeptide comprising an amino acid sequence at least 90% identical to the amino acid sequence encoded by SEQ ID NO:1. 2. The nucleic acid of claim 1 , wherein the polypeptide comprises the amino acid sequence encoded by SEQ ID NO:1. 3. An isolated host cell…
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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