Immobilized transaminases and process for making and using immobilized transaminase
US-2015368682-A1 · Dec 24, 2015 · US
Preparation of 1,4-diaminobutane
US8999680B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8999680-B2 |
| Application number | US-201013386169-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 20, 2010 |
| Priority date | Jul 24, 2009 |
| Publication date | Apr 7, 2015 |
| Grant date | Apr 7, 2015 |
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Abstract
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The present invention relates to a novel method for the preparation of 1,4-diaminobutane [DAB]. The method according to the present invention involves at least one biocatalytic step which comprises the biocatalytic production of at least one N-protected precursor of DAB. The present invention also relates to a method for the preparation of DAB involving at least one biocatalytic step, and comprising the steps of a) biocatalytically preparing an N-protected precursor of DAB yielding a—biocatalytic reaction mixture containing the N-protected precursor of DAB, b) recovering the N-protected precursor from the biocatalytic reaction mixture and c) converting the N-protected precursor into DAB. More in particular, the present invention relates to a method for the preparation of DAB, wherein the at least N-protected precursor of DAB is selected from the group consisting of N5-protected ornithine, N-protected DAB, and N-protected 4-aminobutyraldehyde.
First claim
Opening claim text (preview).
The invention claimed is: 1. An in vitro method for the preparation of 1,4-diaminobutane [DAB] comprising a) enzymatically preparing N-acetyl DAB which comprises a step of contacting N 5 -acetyl ornithine with a decarboxylase (EC 4.1.1), or a step of contacting N-acetyl-4-aminobutyraldehyde with an aminotransferase (EC 2.6.1) to produce an enzymatic reaction mixture (b) recovering the N-acetyl-DAB from the enzymatic reaction mixture, and (c) converting the recovered-N-acetyl-D…
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Classifications
- C12P13/001Primary
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
- C12P13/02Primary
Chemistry & Metallurgy · mapped topic
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- What does patent US8999680B2 cover?
- The present invention relates to a novel method for the preparation of 1,4-diaminobutane [DAB]. The method according to the present invention involves at least one biocatalytic step which comprises the biocatalytic production of at least one N-protected precursor of DAB. The present invention also relates to a method for the preparation of DAB involving at least one biocatalytic step, and compr…
- Who is the assignee on this patent?
- Wu Liang, Raemakers-Franken Petronella Catharina, Dsm Ip Assets Bv
- What technology area does this patent fall under?
- Primary CPC classification C12P13/001. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).