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Filaggrin
US8999635B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8999635-B2 |
| Application number | US-9749306-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 15, 2006 |
| Priority date | Dec 15, 2005 |
| Publication date | Apr 7, 2015 |
| Grant date | Apr 7, 2015 |
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Abstract
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The present invention relates to the identification of loss-of-function mutations in the filaggrin gene and their use in diagnosing ichthyosis vulgaris and/or susceptibility to other diseases including atopic dermatitis (eczema), asthma, psoriasis and allergies (including food allergy).
First claim
Opening claim text (preview).
The invention claimed is: 1. A method for detecting ichthyosis vulgaris or a predisposition to ichthyosis vulgaris in a human subject comprising the step of: detecting in a sample of nucleic acid from the subject the presence of a R501X mutation in the filaggrin gene using one or more of the primers selected from SEQ ID NO: 9, 10, 11, or 12; and correlating the presence of the R501X mutation in the sample with detection of ichthyosis vulgaris or a predisposition to ichthyosis vu…
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Human Necessities · mapped topic
Physics · mapped topic
Physics · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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- What does patent US8999635B2 cover?
- The present invention relates to the identification of loss-of-function mutations in the filaggrin gene and their use in diagnosing ichthyosis vulgaris and/or susceptibility to other diseases including atopic dermatitis (eczema), asthma, psoriasis and allergies (including food allergy).
- Who is the assignee on this patent?
- Mclean William Henry Irwin, Smith Frances Jane Dorothy, Univ Dundee
- What technology area does this patent fall under?
- Primary CPC classification C12Q1/6883. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).