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Methods for treating multiorgan, systemic degos' disease with a complement inhibitor
US8999340B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8999340-B2 |
| Application number | US-201113582018-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 1, 2011 |
| Priority date | Mar 1, 2010 |
| Publication date | Apr 7, 2015 |
| Grant date | Apr 7, 2015 |
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Abstract
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The present disclosure relates to, inter alia, compositions containing an inhibitor of human complement and/or an inhibitor of interferon alpha, and the use of the compositions in methods for treating or preventing Degos' disease in a subject. In some embodiments, the inhibitor is an antibody, or antigen-binding fragment thereof, that binds to a human complement component C5 protein or to a biologically-active fragment of C5 such as C5a or C5b. In some embodiments, the inhibitor is an antibody, or an antigen-binding fragment thereof, that binds to interferon alpha or to an interferon alpha receptor.
First claim
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What is claimed is: 1. A method for treating a patient afflicted with Degos' disease, the method comprising administering an antibody, or antigen-binding fragment thereof, that binds to a human complement component C5 protein, to a patient afflicted with Degos' disease, in an amount sufficient to treat the disease or lessen the severity of one or more symptoms of the disease, wherein the Degos' disease is multiorgan, systemic Degos' disease and wherein the one or more symptoms is s…
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- What does patent US8999340B2 cover?
- The present disclosure relates to, inter alia, compositions containing an inhibitor of human complement and/or an inhibitor of interferon alpha, and the use of the compositions in methods for treating or preventing Degos' disease in a subject. In some embodiments, the inhibitor is an antibody, or antigen-binding fragment thereof, that binds to a human complement component C5 protein or to a bio…
- Who is the assignee on this patent?
- Magro Cynthia, Alexion Pharma Inc
- What technology area does this patent fall under?
- Primary CPC classification A61K38/1725. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).