Polypeptides and antibodies derived from chronic lymphocytic Leukemia cells and uses thereof

US8999328B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8999328-B2
Application numberUS-201113072470-A
CountryUS
Kind codeB2
Filing dateMar 25, 2011
Priority dateDec 8, 2000
Publication dateApr 7, 2015
Grant dateApr 7, 2015

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Abstract

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Small animal models for assessing immunomodulatory effects of compounds are provided.

First claim

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The invention claimed is: 1. A method for treating chronic lymphocytic leukemia (CLL), said method comprising administering to a patient suffering from CLL an antibody, or an antigen-binding fragment thereof, that binds to OX-2/CD200 and comprises a light chain CDR1 having the sequence set forth in residues 26-36 of SEQ ID NO:209; a light chain CDR2 having the sequence set forth in residues 52-58 of SEQ ID NO:209; a light chain CDR3 having the sequence set forth in residues 91-99 o…

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What does patent US8999328B2 cover?
Small animal models for assessing immunomodulatory effects of compounds are provided.
Who is the assignee on this patent?
Bowdish Katherine S, Kretz-Rommel Anke, Alexion Pharma Inc
What technology area does this patent fall under?
Primary CPC classification C07K16/2803. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).