Methods for treatment of cancer with an anti-tigit antagonist antibody
US-2024424092-A1 · Dec 26, 2024 · US
US8999328B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8999328-B2 |
| Application number | US-201113072470-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 25, 2011 |
| Priority date | Dec 8, 2000 |
| Publication date | Apr 7, 2015 |
| Grant date | Apr 7, 2015 |
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Small animal models for assessing immunomodulatory effects of compounds are provided.
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The invention claimed is: 1. A method for treating chronic lymphocytic leukemia (CLL), said method comprising administering to a patient suffering from CLL an antibody, or an antigen-binding fragment thereof, that binds to OX-2/CD200 and comprises a light chain CDR1 having the sequence set forth in residues 26-36 of SEQ ID NO:209; a light chain CDR2 having the sequence set forth in residues 52-58 of SEQ ID NO:209; a light chain CDR3 having the sequence set forth in residues 91-99 o…
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
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Chemistry & Metallurgy · mapped topic
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