Field effect based nanosensor for biopolymer manipulation and detection

Patent metadata

Field	Value
Publication number	US-8999130-B2
Application number	US-201313969997-A
Country	US
Kind code	B2
Filing date	Aug 19, 2013
Priority date	Nov 30, 2012
Publication date	Apr 7, 2015
Grant date	Apr 7, 2015

Abstract

A mechanism is provided for manipulating a molecule. The molecule is driven into a nanochannel filed with electrically conductive fluid. A first vertical electric field is created inside the nanochannel to slow down the molecule and/or immobilize the molecule. The molecule is stretched into non-folded linear chains by the first vertical electric field and a horizontal electric field. Monomers of the molecule are sequentially read.

First claim

What is claimed is:

1. A method for manipulating a molecule, the method comprising:
driving the molecule into a nanochannel filed with electrically conductive fluid;
creating, by a first pair of trapping electrodes, a first vertical electric field inside the nanochannel to at least one of: slow down the molecule and immobilize the molecule;
wherein the first pair of trapping electrodes are positioned to the nanochannel and comprise a first top electrode and a first bottom elec…

Assignees

• IBM

Inventors

• Royyuru Ajay K
• Wang Chao

Classifications

• G01N33/68

  Physics · mapped topic

• G01N27/44791 Primary

  Physics · mapped topic

• G01N33/48721

  Physics · mapped topic

• B82Y15/00

  Operations & Transport · mapped topic

• Y10S977/962

  Cross-Sectional Technologies · mapped topic