Compositions and methods for accurately identifying mutations
US-2024409996-A1 · Dec 12, 2024 · US
US8994946B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8994946-B2 |
| Application number | US-201213725085-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 21, 2012 |
| Priority date | Feb 19, 2010 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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An analytical assembly within a unified device structure for integration into an analytical system. The analytical assembly is scalable and includes a plurality of analytical devices, each of which includes a reaction cell, an optical sensor, and at least one optical element positioned in optical communication with both the reaction cell and the sensor and which delivers optical signals from the cell to the sensor. Additional elements are optionally integrated into the analytical assembly. Methods for forming and operating the analytical system are also disclosed.
Opening claim text (preview).
What is claimed is: 1. An analytical device comprising a chip comprising: an array of zero mode waveguides in a transparent material, each zero mode waveguide having a sample within it, and each zero mode waveguide connected to a fluid conduit for bringing fluid to the zero mode waveguide, the fluid conduit surrounded by an opaque material preventing illumination light from entering the fluid conduit and preventing illumination light from entering a zero mode waveguide from above;…
Operations & Transport · mapped topic
Physics · mapped topic
Physics · mapped topic
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