Operating a mass spectrometer utilizing mass spectral database search
US-2024230661-A1 · Jul 11, 2024 · US
Analyzing target analytes in a sample using mass spectroscopy
US8993958B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993958-B2 |
| Application number | US-201313895738-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 16, 2013 |
| Priority date | May 17, 2012 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Abstract
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A method for determining an amount of an analyte in a sample by mass spectrometry can include the steps of (i) ionizing an analyte from the sample and a deuterated analog of the analyte, to produce an analyte ion and a deuterated analog ion, where the deuterated analog undergoes fragmentation and deuterium scattering during mass spectrometry; (ii) measuring an analyte ion signal and a deuterated analog ion signal by mass spectrometry, where the deuterated analog ion signal is measured using a mass transition resulting from fragmentation and deuterium scattering; and (iii) determining an amount of analyte in the sample using the analyte ion signal and the deuterated analog ion signal. Corresponding kits can include instructions for carrying out the method, together with a deuterated analog of the analyte selected to undergo fragmentation and deuterium scattering during mass spectrometry and exhibit a mass transition resulting from fragmentation and deuterium scattering.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method for determining an amount of an analyte in a sample by mass spectrometry, the method comprising: ionizing an analyte from the sample and a deuterated analog of the analyte to produce an analyte ion and a deuterated analog ion, wherein the deuterated analog undergoes fragmentation and deuterium scattering during mass spectrometry; selecting a mass transition resulting from fragmentation and deuterium scattering of the deuterated analog; mea…
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Classifications
- H01J49/0036Primary
Electricity · mapped topic
Physics · mapped topic
Electricity · mapped topic
- G01N33/6851Primary
Physics · mapped topic
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Frequently asked questions
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- What does patent US8993958B2 cover?
- A method for determining an amount of an analyte in a sample by mass spectrometry can include the steps of (i) ionizing an analyte from the sample and a deuterated analog of the analyte, to produce an analyte ion and a deuterated analog ion, where the deuterated analog undergoes fragmentation and deuterium scattering during mass spectrometry; (ii) measuring an analyte ion signal and a deuterate…
- Who is the assignee on this patent?
- Eastwood Martin, Micromass Ltd
- What technology area does this patent fall under?
- Primary CPC classification H01J49/0036. Mapped technology areas include Electricity.
- When was this patent published?
- Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).