Process for preparing 5-biphenyl-4-amino-2-methyl pentanoic acid
US-9206116-B2 · Dec 8, 2015 · US
US8993785B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993785-B2 |
| Application number | US-201414224700-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 25, 2014 |
| Priority date | Jan 12, 2007 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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The present invention relates to pyrrolidin-2-ones according to the formula (1), or salts thereof, wherein R1 is hydrogen or a nitrogen protecting group, methods for their preparation and their use in the preparation of NEP-inhibitors, particularly in the preparation of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester or salt thereof.
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The invention claimed is: 1. A compound selected from the group consisting of a) a compound according to formula (2), or tautomer, or salt thereof, wherein R1 is hydrogen or a nitrogen protecting group, b) a compound according to formula (13), or tautomer, or salt thereof,…
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