Process for manufacture of telmisartan

US8993778B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8993778-B2
Application numberUS-201313750551-A
CountryUS
Kind codeB2
Filing dateJan 25, 2013
Priority dateMar 31, 2003
Publication dateMar 31, 2015
Grant dateMar 31, 2015

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

A process for preparing telmisartan by reacting 2-n-propyl-4-methyl-6-(1′-methylbenzimidazol-2′-yl)benzimidazole with a compound of formula (IV) wherein Z is a leaving group, to obtain the compound 2-cyano-4′-[2″-n-propyl-4″-methyl-6″-(1′″-methylbenzimidazol-2′″-yl)benzimidazol-1″-ylmethyl]biphenyl, and subsequently hydrolyzing the nitrile function to obtain the acid function.

First claim

Opening claim text (preview).

We claim: 1. A process for preparing telmisartan, comprising: (a) reacting 2-n-propyl-4-methyl-6-(1′-methylbenzimidazol-2′-yl)benzimidazole (I): with a compound of formula (IV): wherein Z is a leaving group, in a first solvent selected from methylene chloride…

Assignees

Inventors

Classifications

  • Human Necessities · mapped topic

  • Human Necessities · mapped topic

  • C07D235/20Primary

    Chemistry & Metallurgy · mapped topic

  • Chemistry & Metallurgy · mapped topic

  • C07D403/04Primary

    Chemistry & Metallurgy · mapped topic

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What does patent US8993778B2 cover?
A process for preparing telmisartan by reacting 2-n-propyl-4-methyl-6-(1′-methylbenzimidazol-2′-yl)benzimidazole with a compound of formula (IV) wherein Z is a leaving group, to obtain the compound 2-cyano-4′-[2″-n-propyl-4″-methyl-6″-(1′″-methylbenzimidazol-2′″-yl)benzimidazol-1″-ylmethyl]biphenyl, and subsequently hydrolyzing the nitrile function to obtain the acid …
Who is the assignee on this patent?
Hauel Norbert, Dach Rolf, Heitger Helmut, and 2 more
What technology area does this patent fall under?
Primary CPC classification C07D235/20. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).