Acrylamide compounds and use thereof for inhibiting apoptosis
US-9199978-B2 · Dec 1, 2015 · US
Tropolone compounds for treating or preventing retroviral infection
US8993768B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993768-B2 |
| Application number | US-201214116423-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 10, 2012 |
| Priority date | May 11, 2011 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Abstract
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Disclosed are compounds that inhibit RNase H activity of retroviruses, for example, a compound of formula (I) wherein R 1 , R 2 , and R 3 are as described herein, as well as pharmaceutically acceptable salts, solvates, stereoisomers, and prodrugs thereof. Pharmaceutical compositions comprising such compounds, as well as methods of use, and treatment or prevention of infection by human immunodeficiency virus (HIV).
First claim
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The invention claimed is: 1. A compound of formula I: wherein R 1 is selected from the group consisting of H, heterocyclyl C 1 -C 6 alkyl, C 1 -C 6 alkylamino C 1 -C 6 alkyl, C 1 -C 6 dialkylamino C 1 -C 6 alkyl, C 6 -C 14 aryl C 1 -C 6 alkylamino, C 6 -C 14 aryl C 1 -C 6 alkylamino C 1 -C 6 alkyl, C 6 -C 14 aryl amino C 1 -C 6 alkyl, C 1 -C 6 alkylthio…
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Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US8993768B2 cover?
- Disclosed are compounds that inhibit RNase H activity of retroviruses, for example, a compound of formula (I) wherein R 1 , R 2 , and R 3 are as described herein, as well as pharmaceutically acceptable salts, solvates, stereoisomers, and prodrugs thereof. Pharmaceutical compositions comprising such compounds, as well as methods of use, and treatment or prevention of infection by human immunode…
- Who is the assignee on this patent?
- Beutler John A, Legrice Stuart F J, Thomas Craig, and 4 more
- What technology area does this patent fall under?
- Primary CPC classification A61K31/4453. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).