Modulators of toll-like receptor 7

Patent metadata

Field	Value
Publication number	US-8993755-B2
Application number	US-201414158595-A
Country	US
Kind code	B2
Filing date	Jan 17, 2014
Priority date	Jun 29, 2007
Publication date	Mar 31, 2015
Grant date	Mar 31, 2015

Abstract

The present application includes a compound of Formula I or II:

or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods that include the administration of such compounds with at least one additional active agent.

First claim

What is claimed:

1. A compound represented by Formula Ia:

or a pharmaceutically acceptable salt thereof, wherein:
R 1 is selected from the group consisting of

R 2 is H;
-L 3 -R 3 is —OCH 2 CH 2 OCH 3 , —OCH 2 CH 2 CH 3 , —OCH 2 CH 2 CH 2 CH 3…

Assignees

• Gilead Sciences Inc

Inventors

• Graupe Michael
• Halcomb Randall L

Classifications

• A61P31/12

  Human Necessities · mapped topic

• A61P31/14

  Human Necessities · mapped topic

• A61P31/20

  Human Necessities · mapped topic

• A61P31/00

  Human Necessities · mapped topic

• A61P43/00

  Human Necessities · mapped topic