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Method for preparation of the tetrasaccharide lacto-N-neotetraose (LNnt) containing N-acetyllactosamine
US8993740B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993740-B2 |
| Application number | US-201113579741-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 21, 2011 |
| Priority date | Feb 19, 2010 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Abstract
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The present invention relates to a method for preparation of the tetrasaccharide lacto-N-neotetraose (LNnt, formula (I)) especially in large scale, as well as intermediates in the synthesis, a new crystal form (polymorph) of LNnt, and the use thereof in pharmaceutical or nutritional compositions.
First claim
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The invention claimed is: 1. A polymorph of Galpβ1-4GlcNAcpβ1-3Galpβ1-4Glc (LNnT), characterized in that it displays X-ray powder diffraction reflections, based on a measurement using CuKα radiation, at 20.32±0.20, 19.10±0.20, 7.98±0.20, 21.03±0.20, 20.95±0.20 and 5.66±0.20 2Θ angles. 2. The polymorph of Galpβ1-4GlcNAcpβ1-3Galpβ1-4Glc according to claim 1 , which displays a melting point between 226-230° C. 3. A pharmaceutical composition co…
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Human Necessities · mapped topic
- C07H1/00Primary
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
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- What does patent US8993740B2 cover?
- The present invention relates to a method for preparation of the tetrasaccharide lacto-N-neotetraose (LNnt, formula (I)) especially in large scale, as well as intermediates in the synthesis, a new crystal form (polymorph) of LNnt, and the use thereof in pharmaceutical or nutritional compositions.
- Who is the assignee on this patent?
- Bajza István, Dekany Gyula, Ágoston Károly, and 16 more
- What technology area does this patent fall under?
- Primary CPC classification C07H1/00. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).