Parp inhibitor containing piperazine structure, preparation method therefor and pharmaceutical use thereof
US-2024336624-A1 · Oct 10, 2024 · US
US8993632B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993632-B2 |
| Application number | US-201213469021-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 10, 2012 |
| Priority date | Jan 5, 2005 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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The present invention relates to inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme and their use in treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, central nervous system disorders, and diseases and conditions that are related to excessive glucocorticoids.
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What is claimed is: 1. A method for treating a patient suffering from a disorder selected from the group consisting of neuropathy, neuronal dysfunction, decline in cognitive function in Alzheimer's disease and associated dementias, attention deficit disorder in general, attention deficit hyperactivity disorder (ADHD), mild cognitive impairment, steroid-induced acute psychosis, schizophrenia, and combinations thereof, comprising administering to the patient an effective amount of a…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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