Gpx4 inhibitors, pharmaceutical compositions thereof, and their use for treating gpx4-mediated diseases
US-2024246901-A1 · Jul 25, 2024 · US
US8993602B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993602-B2 |
| Application number | US-201214008332-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 27, 2012 |
| Priority date | Mar 29, 2011 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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The invention relates to a benzoic acid salt of methyl(2R,3R)-2-{3-[amino(imino)methyl]benzyl}-3-{[4-(1-oxidopyridin-4-yl)benzoyl]amino}butanoate, and to a benzoic acid salt of methyl(2R,3R)-2-{3-[amino(imino)methyl]benzyl}-3-{[4-(1-oxidopyridin-4-yl)benzoyl]amino}butanoate which is in a crystalline form or in at least partially crystalline form, as well as a process for the preparation of the same, methods of using such salt to treat subjects suffering from conditions which can be ameliorated by the administration of an inhibitor of Factor Xa.
Opening claim text (preview).
The invention claimed is: 1. Benzoic acid salt of methyl(2R,3R)-2-{3-[amino(imino)methyl]benzyl}-3-{[4-(1-oxidopyridin-4-yl)benzoyl]amino}butanoate. 2. Benzoic acid salt according to claim 1 which is in a crystalline form or in at least partially crystalline form. 3. Benzoic acid salt according to claim 2 wherein the crystalline salt exhibits in an X-ray powder diffraction pattern measured in transmission with CuKα 1 radiation at room te…
Human Necessities · mapped topic
Human Necessities · mapped topic
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