Asgpr-binding compounds for the degradation of extracellular proteins
US-2024424108-A1 · Dec 26, 2024 · US
US8993600B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993600-B2 |
| Application number | US-11493508-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 5, 2008 |
| Priority date | Nov 8, 2005 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
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What is claimed is: 1. A pharmaceutical composition comprising: (i) an effective amount of the compound: or a pharmaceutically acceptable salt thereof; and (ii) a pharmaceutically acceptable carrier.
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