Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
US-2015368246-A1 · Dec 24, 2015 · US
Carboxamide heterocyclic CGRP receptor antagonists
US8993588B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993588-B2 |
| Application number | US-60267608-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 2, 2008 |
| Priority date | Jun 5, 2007 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Abstract
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Compounds of formula I: wherein variables A 1 , A 2 , B, m, n, J, R 4 , G 1 , G 2 , G 3 and Y are as described herein, which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
First claim
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What is claimed is: 1. A compound of formula I: wherein: B is selected from the group consisting of phenyl, thienyl, pyridinyl, isoquinolinyl, tetrahydroisoquinolinyl, naphthyl, isoxazolyl, indolyl, piperidinyl, tetrahydrofuranyl, piperazinyl, pyrazolyl and pyrrolidinyl (which is optionally substituted with oxo), wherein B is unsubstituted or substituted with 1-5 subst…
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- C07D471/20Primary
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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- What does patent US8993588B2 cover?
- Compounds of formula I: wherein variables A 1 , A 2 , B, m, n, J, R 4 , G 1 , G 2 , G 3 and Y are as described herein, which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the …
- Who is the assignee on this patent?
- Bell Ian, Selnick Harold, Zartman C Blair, and 1 more
- What technology area does this patent fall under?
- Primary CPC classification C07D471/20. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).